My cat got an accidental double dose of buprenex. Is she okay?

With your cat's weight being 11 pounds, there is a dose range for Buprenorphine that fits into the amount you gave. He may be a little sleepier and I would not continue the double dose unless your vet recommends it. Keep an eye on him in case he is too sleepy, but he should be ok. Signs of a problem would be too sleepy, a slower breathing rate.

This represents a pretty substantial overdose. Corbett got about 2.5 times more than the highest published dose for pain relief. However, it's thought that buprenorphine has a high index of safety, and even large overdoses don't usually cause serious effects. I'm assuming you gave it on the gums ("transmucousally") as that's how it's typically prescribed for pain relief at home in cats. Because of that method of administration, there's no way to remove the drug from his system by inducing vomiting. There is a reversal agent that is somewhat effective, but may have to be given in multiple doses due to the way buprenorphine works. The drug is naloxone, and your veterinarian should have this drug. Because the signs of overdose can be concerning (vocalization, ataxia, hypersalivation, decreased body temperature, and lethargy) my best recommendation would be for you to take Corbett back to your veterinarian for administration of this drug, so that the overdosage can be averted.

Hi, the sedative effects described are expected with the high dose Maggie received. The good news is that they should wear off over the next few hours and within 4 hours she should be more alert and almost back to normal. If you are worried though please have her checked over !

Buprenorphine often causes sedation as a side effect - sometimes a lot of sedation, as sounds like the case with Lady! The dose she received (0.3 mg for a 25 pound dog) is within the normal dosage range, and should not be expected to cause any serious problems at all :) The sedation should wear off in the next 6-8 hours, or possibly even sooner as the drug levels in her body start to drop. Buprenorphine has no negative impact on the pancreas at all, and is very commonly used for pain control in dogs with pancreatitis. I hope Lady starts to feel better soon!

I am sorry we couldn't get to your question earlier. Hopefully Sitara is back to normal now. The symptoms you have described are consistent with opioid use (which is what Buprenorphine is). I would not be overly concerned. I am more concerned about her dental disease and the plan to treat that, since the pain medications and antibiotics won't fix that particular problem. She needs a full dental cleaning under anesthesia and may need her teeth extracted if stomatitis is a concern. https://www.petcoach.co/article/gingivitis-and-stomatitis-in-cats/

Hello, Gabapentin is a pain medication commonly prescribed to pets after surgery. Mild sedation can be noticed as a side effect, often due to the pain relief allowing the pet to get rest. Dosing should be given every 8-12 hours as needed. As she had her last dose over 12 hours ago, any side effects should be starting to wear off and will continue to do so if the medication is not repeated. I hope this helps. Thanks for using Petco Pet Education Center, formerly Petcoach.

Buprenorphine has few side effects in cats with the most common one being sedation. It may be Sofia is feeling a bit nauseous from vomiting, which can happen. If you are very concerned about her, you can take her into the vet. Best of luck.