What are the dangers if my cat misses a day or two of prednisone?

It would help to know what medical condition she is taking the steroid for - if she has a life-threatening auto-immune disease, for example, then I would definitely not want to skip any doses since this could cause a relapse of her disease. But if she is taking the steroid for allergies or some other condition that is not as serious, then it would probably not cause any harm if she misses a dose or two - you might see some recurrence of her symptoms, but this would not seriously jeopardize her health. It would also help to know specifically what steroid she was taking (prednisolone, dexamethasone, etc) since different medications stay in the system longer than others. If you want to post again with more details, we can try to give a more specific answer.

It depends how long he was on it. If he was on it for less than a week, you can stop it cold turkey. If it was longer than that, you can respectfully tell the vet that you are concerned about iatrogenic (meaning medical treatment caused the issue) Addison's disease (underactive adrenal gland). Thanks for asking Petco Pet Education Center, formerly Petcoach!

Cats are normally very resistant to the side effects of Prednisone, so the signs you are describing are very usual to see in cats. Was Elliot started on any other medications that may be causing these symptoms? I would definitely discuss any changes in his Prednisone dosing with his veterinarian. Sometimes we can get away with lower doses, but need to decrease the amounts carefully. We normally do not recommend decreasing the amount by more than 50% at a time, so decreasing from 1 mL twice daily to 0.5 mL once daily would be decreasing the dose by four times, which might be too extreme for Elliot (even after only 6 days on the steroid). The good news is that we do not tend to see heart problems with oral steroids (only injectible steroids), so you do not need to worry about heart problems with oral steroids. I hope that answered your question. Thanks for using Petco Pet Education Center, formerly Petcoach.

If he was on 12mg of prednisolone for 10 days straight and then it was suddenly stopped, then yes that could be part of the problem, but its also possible that he is still ill from the original disease. I would strongly recommend that you take to your veterinarian; it would be useful to recheck a physical exam and some blood tests. They may recommend running a baseline cortisol to ensure that stopping the pred is not the cause of current symptoms. Thank you for asking Petco Pet Education Center, formerly Petcoach!

I do not recommend giving any pets any human medications without specific instructions from your vet. Steroids have to be given carefully in order to obtain the correct therapeutic effect and they must be weaned off it when finishing a course. This is a discussion best handled by your veterinarian.

Given her age, steroid side effects from long term use tend to become less of a risk if the benefits are clearly improving her quality of life. Depending on the nature of the growth, low level chemotherapy medications may provide an opportunity to halt growth or even reduce the mass but this would require assessment by a specialist

Your dog should be weaned off Prednisone slowly. In many ways, prednisone is similar to the corticosteroid hormones cortisol and aldosterone produced by the adrenal glands located along each kidney. Because of this, when taking prednisone, the adrenal glands start decreasing their production of cortisol. It would be too shocking for the adrenal glands to find themselves out of the blue in need of producing cortisol in large amounts again, so by tapering the prednisone gradually, the glands are given some time to resume their normal function. The main risk is what is called an " addisonian crisis" or "iatrogenic hypoadrenocorticism" which can be life threatening and can cause the dog to go into shock. This can happen when the prednisone is stopped out of the blue and the adrenal glands are dormant because they weren't given a chance to gradually become active again. When this happens, the dog's potassium and sodium levels get unbalanced. The sodium levels start to fall, while the potassium levels start to rise. High potassium levels can have a detrimental effect on the heart and can lead to circulatory collapse. Affected dogs may appear weak, lethargic, they may vomit, have a low, irregular heart rate and may go into shock and even collapse. Affected dogs need to seek immediate emergency treatment to correct the electrolyte imbalances and possible low glucose levels through supportive care consisting of fluid therapy and careful monitoring. Rapidly-acting corticosteroid medications such as prednisolone sodium succinate or dexamethasone sodium phosphate may be needed. This whole ordeal can be easily prevented by gradually tapering the dog off the steroids. Dogs on prednisone for quite some time, need to be tapered even more gradually. The vet will tell owners how.