Why is my cat lethargic, not eating, and has high liver enzymes?

Although we can not prescribe treatment via an online method (illegal with our veterinary licenses), what i can tell you is that an ultrasound can not assess liver function. Ultrasound is just an image so it can tell you size and texture changes to organs and evaluate for masses, fluid, etc. Also the good appetite and energy level are not typical with liver failure. Your cat has elevated liver enzymes and total bilirubin but this does not always mean liver failure. I would try to get better clarification from your vet about what was seen on the ultrasound and were the other organs normal (pancreas, GI tract, etc.). More common causes of these bloodwork changes would include liver/biliary infection, pancreatitis, and underlying GI disease associated with the above. Cancer and certain infectious diseases such as FIP can as well. So options would include additional testing to search for a cause (such as pancreatitis testing, liver aspirates, etc.) and/or symptomatic treatment can be attempted for pancreatitis, liver infection, etc. I hope this helps and thank you for using Petco Pet Education Center, formerly Petcoach!

It is unlikely that diet alone is the cause of significant decrease to liver function. I would agree that Royal Canin and Hill's are not very different in terms of dietary quality. I feel that starting on a liver diet at this point based on one blood test is very premature and that further diagnostics are likely warranted. Some possible causes of increased liver values including endocrine conditions, liver shunts, hepatitis, bile duct / gall bladder issues, liver / gall bladder tumors, or fatty liver disease. Depending on the nature and magnitude of the elevation, it may be insignificant as well if Maki's findings were not coupled with any clinical signs of illness. Some additional diagnostic testing to look into things more would be additional more specific blood work, radiographs, and ultrasound. Rather than dietary change, there are more target liver supplements. One that comes to mind is called Denamarin. There is a feline formulation available that would work fine. Hope this helps.

Hello, I am sorry to hear about Patches. The blood work that you’ve attached shows that Patches liver enzymes are elevated. There are a variety of causes for elevated liver enzymes including infection, inflammation, old age change, etc. Liver disease can definitely make dogs feel nauseous and have an altered appetite. If Patches is not acting like himself I would recommend having him evaluated by a veterinarian again. Having an abdominal ultrasound performed might be a helpful test as it would allow further evaluation of the liver. I hope this helps, good luck!

Poor guy. It is tough when you are in these situations where you are deciding on continued care (which isn’t 100% guarantees to work) or Humane euthanasia. Unfortunately we don’t have enough information about your cats particular case to help you decide things here. Perhaps a consultation would be best to comb through all of the details such as lab work findings (even seeing the normals is quite helpful), medications tried so far, and his physical exam findings would also be helpful. But generally speaking if your pet is ill from liver disease, which can be any condition such as hepatitis, hepatic lipidosis (carries a poorer prognosis unless aggressive treatment is implemented including a feeding tube in most situations), liver cancer or even gallbladder disease can cause elevated liver enzymes, then it’s best fo an abdominal ultrasound to determine what specific liver condition is present. The prognosis of your pet should be determined by your vet and then carefully considered when determining if continued care should be done or if Humane euthanasia is the better option. I hope this helps and best wishes moving forward with a good decision regarding Elmo’s care.

Hello and welcome to Petco Pet Education Center, formerly Petcoach. Hepatitis (infection and inflammation of liver) is a very serious condition and is very hard to treat. If there is an internal medicine specialist in the area I would recommend having Nala seen by them. Otherwise I would be talking with your vet about testing for infectious diseases. However, it looks like they have treated her with broad spectrum antibiotics as well as IV fluids. I would recommend continuing treatment. She may need a feeding tube placed to try to keep her protein up during this illness. Unfortunately, with how severe this is, she may or may not pull through it, but the best chance of her making it through is to be aggressive with her treatment. I would suggest continuing to monitor her liver and white cell count, and to have imaging done and possible samples of her liver to try to determine the cause of the infection. Otherwise I would be talking to your vet about the parasites and infections present in your area and get covered with certain antibiotics. The white cells have increased however not that much, and the liver enzymes are actually improving if I can read the dates right from your picture. This is very hopeful. I would continue with antibiotics (IV if you cannot get them in orally), as well as IV fluids and I would think about syringe feeding or placing a feeding tube. Best of luck with Nala, I hope she makes a good recovery.

Thanks for using Petco Pet Education Center, formerly Petcoach! Loss of appetite can be observed with many conditions such as gastroenteritis, dietary indiscretion, kidney disease, pancreatitis, among many other possibilities. I am more concerned about the fact that she is not eating well and that needs to be further addressed as it is unlikely to be due to a urinary tract infection. I recommend that you have Luchadora reevaluated by your veterinarian on Saturday for further assessment and treatment. Keep in mind that if she is not feeling well, they may not proceed with vaccines that day. You may take in a urine sample that day. They would be able to check for these possibilities and others depending on the findings on exam. Treatment would be based on findings. Good luck and have a great day! Hoping for a speedy recovery!

Hi there and thank you for using Petco Pet Education Center, formerly Petcoach to address your concern. I am sorry to hear that Kitty is not feeling very well. With the description and blood results, I worry about a condition known as hepatic lipidosis (fatty liver disease) or triaditis (inflammation of the pancreas, liver and small intestines). For fatty liver disease, a feeding tube is generally recommended to help bring cats out of this condition as nutritional support is key and extremely important in these cases. I would recommend an abdominal ultrasound as the next diagnostic step to help better determine what the cause could be. If Kitty is still not wanting to eat, you need to consider hospitalization and feeding tube placement to help her get through this. I hope this helps guide you in the right direction. Please let me know if you have any other questions or concerns and I would be more than happy to help you further.