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My cat has Frontline Plus. Can I add a Seresto collar safely?

Updated on September 23rd, 2025

Pet's info: Cat | Mixed Breed | Male | neutered

Hi! Can Frontline Plus and Seresto be safely combined for a medium/large cat? He’s had Frontline Plus administered two weeks ago for fleas, and I’m specifically wondering whether a Seresto collar can safely be used for supemental protection — especially when he goes outside, and while I’m working to get the house flea-free — before the next monthly dose of Frontline. Thanks!

1 Answer

Most Helpful Answer

Linda G,  MS, DVM

Answered By Linda G, MS, DVM

Veterinarian

Published on February 12th, 2019

Hello. Yes, absolutely you can use both, but since the collar lasts 8 months, remove it for a week after you reapply the Frontline Plus. Then you can safely put the collar back on. Thanks for using Petco Pet Education Center, formerly Petcoach.
Vote Icon56Pet Parents found this answer helpful

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