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Cat on Efex for ear infection: Is 42 days too long, risking blindness?

Updated on September 23rd, 2025

Hello! My vet prescribed Efex (marbofloxacin) for one of our cats experiencing issues with balance, after diagnosing the problem as otitis interna. However, the duration of treatment is 42 days, and I read that fluoroquinolones should not be given to cats for long periods because it can cause blindness. Now I'm worried and, thus, writing to you to ask for a second opinion. Should I worry? Aren't there any safer antibiotics to give long term that I can discuss with the vet? Thanks!

1 Answer

Most Helpful Answer

Linda G,  MS, DVM

Answered By Linda G, MS, DVM

Veterinarian

Published on September 5th, 2019

Hello. I would be very cautious about using the Efex for such a long period of time. Our veterinary formulary says the maximum use in cats should not exceed 30 days, but even at this time frame, you can still wind up with side effects from the long term use of any flouroquinolone, or run into a problem with antibiotic resistance. If the otitis interna was definitively diagnosed by radiography & myringotomy & this antibiotic was chosen based on a culture & sensitivity, then I would administer the antibiotic with frequent rechecks. Otherwise, an MRI may be necessary to confirm the condition. This may be the antibiotic to use, but 42 days is a bit worrisome. Thanks for using Petco Pet Education Center, formerly Petcoach.
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