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Why does my cat have chronic explosive diarrhea despite treatments?

Updated on September 23rd, 2025

Pet's info: Cat | Domestic Shorthair | Female | spayed | 12 years and 11 months old

My cat has had chronic diahrea for at least a month. I have wormed her & she has been on antibiotics for 6. She goes at least twice a day & it is massive & pure liquid but explosive. It is a normal colour & she appears well otherwise. I have tried changing her diet although this has been difficult with other cats, as she prefers their food

1 Answer

Most Helpful Answer

Sarah Derksen, DVM

Answered By Sarah Derksen, DVM

Veterinarian

Published on September 25th, 2018

Hi. Poor Misty. Many times plder kitties can have diarrhea from 2 of the most common causes. Irritable bowel syndrome, or GI lymphoma (gastrointestinal cancer). Unfortunately that is on the list due to age. Of course parasites or overgrowth of bacteria should be ruled out by a fecal float and culture. As far as IBS, the signs can be just like your kitties. It is treated via a diet change to a prescription bland food, and steroids. Lymphoma looks exactly alike, except it doesn't respond to treatment as long as IBS. The only way to definitively diagnose is a GI biopsy. That is onvioulsy intense. So many choose to do the diet and steroids and hope for the best. Others do the biopsy and if cancer, may consult w an oncologist. I would recommend starting with an exam, fecal float, fecal culture, xrays of abdomen, and if all normal, diet change and steroids.
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