Trifexis Prescription Flea & Tick Medicine

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Health & Wellbeing
Simparica Trio vs. Trifexis: Best Flea & Tick Med for Your Dog?
Unsure which flea & tick medication to choose for your pup? Check out our comparison of Simparica Trio vs. Trifexis to see which product will work best for your dog!
Updated on October 29th, 2025
Health & Wellbeing
Interceptor vs. Heartgard: Guide to Heartworm & Worm Prevention
Search Petco to find the benefits of both Interceptor and Heartgard worm medicines for dogs. We strive to help you keep your pup happy and healthy.
Updated on October 29th, 2025
Health & Wellbeing
Stop Fleas, Ticks & Mosquitoes: Pet Pest Prevention for a Healthy Pet
You may have heard that flea and tick prevention are crucial for dogs and cats, but do you know why? Petco is sharing why and how to prioritize pest prevention for your pet.
Updated on October 29th, 2025
New Pet
Protect Your Pet: Flea & Tick Control Solutions for Dogs & Cats
Learn how to remove flea and ticks. Petco has flea and tick removal services for dogs and cats. Get fleas and ticks removed at your neighborhood Petco.
Updated on October 29th, 2025
Health & Wellbeing
Interceptor vs. Interceptor Plus: Best Heartworm & Worm Med for Dogs
At Petco, learn more about the benefits & differences of Interceptor & Interceptor Plus dewormer for dogs with heartworm, roundworms, hookworms & tapeworms.
Updated on October 29th, 2025
Health & Wellbeing
Is Triflex a generic version of flea and tick medicine? My grandma said she used it, but I think she meant Trifexis. I just want to be sure.
Hi, thanks for using Boop by Petco! So there is something called Triflex which is a human joint supplement. It isn't used for flea and ticks. I would ask her again and ask her what she uses the product for. If she is referring to flea and tick prevention she likely just misspoke as there is no generic for Trifexis that I am aware of. Have a good day!
Updated on August 12th, 2025
Health & Wellbeing
My 2 small dogs have been Trifexis for the past 1 to 2 years but last month it stopped working & they're covered in fleas! What should I switch to?
Oh no! Fleas are not a fun surprise! Trifexis prevents fleas, heartworms and some intestinal parasites. Since this isn't working for you, I typically recommend using either Nexgard, Bravecto or K9 Advantix II as flea and tick prevention. Please note that Nexgard and Bravecto are prescription-based (like the Trifexis), so these would need to be obtained by Prince's vet. Prince and his friend will also need to start a separate heartworm prevention, such as Heartgard or Interceptor, but again, these are prescription-based. Until you can pick up these new medications, you can bathe both dogs in original blue Dawn dish soap because this will help to kill the existing adult fleas. I hope this helps and that all goes well!
Updated on August 12th, 2025
Health & Wellbeing
If I give my puppy TriFexis for the various worms and fleas, can I comebine it with anything to protect against ticks as well? TriFexis doesn’t cover ticks. I prefer an oral treatment versus topical or collars. Any recommendations? I can also swap ou
It is generally not recommended to use two oral products together. It's not to say it's impossible but many of these companies have not done the testing to know if there are interactions. You may discuss this with your regular vet to see if they have any experience with this. Most topical flea and tick products are expected to be safe to use with Trifexis. There is also a collar called a Preventic which is fine to use with oral products. Most people only put the collar on the pet when it is going out to tick areas and they remove it when the pet is not in those areas. Another option is to ask your vet if they would exchange the product for something like Simparica and Interceptor which would get all your parasite concerns. Some clients will also switch products when ticks are in season or when exposure is expected and then switch back once the exposure time is over. I hope this is helpful and please feel free to post any additional questions.
Updated on August 12th, 2025
Health & Wellbeing
is there any flea oral medicine similar to comfortis that does not require a vet prescription?
Advantus chews or CapStar may be options for flea control. The only drawback is that they are given daily. Comfortis, Credelio or Trifexis are probably your best options as they are more effective that the daily chews.
Updated on August 12th, 2025
Health & Wellbeing
Hello we are due to update both of our dogs on flea and tick chews.
The easiest way to do so is to go to your veterinarian and either buy the chews from him or get a prescription from your vet and get them over the internet. I am assuming you are looking to buy either Bravecto, Simparica or Nexgard. These are prescription only.
Updated on August 12th, 2025