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Health & Wellbeing
Simparica Trio vs. Trifexis: Best Flea & Tick Med for Your Dog?
Unsure which flea & tick medication to choose for your pup? Check out our comparison of Simparica Trio vs. Trifexis to see which product will work best for your dog!
Updated on January 15th, 2026
Health & Wellbeing
Interceptor vs. Interceptor Plus: Best Heartworm & Worm Med for Dogs
At Petco, learn more about the benefits & differences of Interceptor & Interceptor Plus dewormer for dogs with heartworm, roundworms, hookworms & tapeworms.
Updated on January 15th, 2026
Health & Wellbeing
Interceptor vs. Heartgard: Guide to Heartworm & Worm Prevention
Search Petco to find the benefits of both Interceptor and Heartgard worm medicines for dogs. We strive to help you keep your pup happy and healthy.
Updated on January 15th, 2026
Health & Wellbeing
Selamectin for Dogs & Cats: Stop Fleas, Ticks & Heartworms
Search Petco for information on selamectin for pets of all kinds. We have all the details on how to prevent heartworms & parasites to keep your pet healthy.
Updated on January 15th, 2026
Health & Wellbeing
Fish Oil for Dogs: Benefits, Dosage, & Our Top Supplement Picks
Learn about the benefits of fish oil for dogs. Order online from Petco and save with Repeat Delivery or Curbside Pickup.
Updated on January 15th, 2026
Health & Wellbeing
Revolution out of stock? What's a similar dog all-in-one parasite med?
Simparica Trio is a similar medication that treats fleas, ticks, heartworms, roundworms, and hookworms. It's a chewable tablet rather than a topical, but is easy to give and can help bridge the gap until you're back on your regular medication. It is best to confirm it is safe to give with your vet if Mia has any other underlying health conditions or issues, and your vet can order it or provide a prescription to an online service such as Chewy.
Updated on November 25th, 2025
Health & Wellbeing
My puppy got adult Simparica Trio, adult dog got puppy dose. Help!
Hello and thank you for contacting Boop by Petco. You should monitor Purl for symptoms of vomiting, lethargy, lack of appetite, tremors, problems with balance. If you notice any of these signs, you should get your puppy checked by your local vets right away. According to the manufacturer's data the symptoms are NOT likely to develop after ingesting this dose. You should give your bigger dog another tablet to get the right dose for 22-44 pound weight (that should be 24mg of sarolaner, moxidectinum 0.48mg and pyrantelum 100mg).
Updated on November 25th, 2025
Health & Wellbeing
My dog gets ticks on Simparica. What's best for high-risk areas?
The active ingredient in Simparica is sarolaner. At this time, there are no known drug interactions reported with sarolaner. I would therefore use a spot on treatment for fleas and ticks like Frontline or K9 Advantix II. I hope this helps!
Updated on November 25th, 2025
Health & Wellbeing
Choosing flea, tick, heartworm meds: Revolution, Advantix, Heartgard?
Congratulations on your new dog! I like Revolution if you are looking for a topical product. It consistently works well and is well tolerated. If you like the idea of an oral product better, I like Trifexis (it’s another all in one product). Sometimes though the pets can smell the Trifexis and they won’t eat it. In that instance, I like Simparica and Interceptor. My personal preference is oral products. I hope this helps and please feel free to post any additional questions.
Updated on November 25th, 2025
Health & Wellbeing
My dog ate two Simparica Trio. Should I be worried about overdose?
These products are overall very safe. In all likelihood, nothing will happen. In dogs with a low seizure threshold, it could contribute to seizures. We typically don't recommend inducing vomit unless we know the ingestion will cause harm, as vomit induction has it's own list of side effects. Monitor Karyn at home for 24 hours, and once that time has passed, I would not worry about it any longer.
Updated on November 25th, 2025