Vet Q & AFrontline failed! What topical flea treatments actually work?
I'm sorry you are having such problems with fleas! I have personally found, as have a number of my colleagues, that there is resistance to Frontline and pets continue to have problems with them despite applying the Frontline. I will give you the flea treatment program I typically recommend and have found to be very effective. First, I would give Shadow Capstar. It's a one time pill that starts killing fleas within 30 minutes. Then follow up with a spot on treatment, such as Advantage or Revolution. This is a treatment that has to be used once a month. You will also have to disinfect the environment, this is very important. Wash his bedding in hot soapy water, and vacuum the furniture and carpet surfaces. You can use a spray to kill fleas in the house, such as Indorex, or a flea bomb would work well to kill the fleas in the home. You may have to flea bomb the house a few times to kill all the fleas. My brother had a problem with fleas in his home, and the exterminator had to visit three times before they were all gone. I hope this helps!
Updated on September 24th, 2025