FRONTLINE Cat

Flea-Free Cats: Injectable Prevention for Lasting Protection

Because fleas are so problematic, flea prevention is essential! Commonly prescribed preventives include oral and topical medications—although injectable flea prevention is available, as well.

Updated on April 1st, 2026

Selamectin for Dogs & Cats: Stop Fleas, Ticks & Heartworms

Search Petco for information on selamectin for pets of all kinds. We have all the details on how to prevent heartworms & parasites to keep your pet healthy.

Updated on October 23rd, 2025

Stop Fleas, Ticks & Mosquitoes: Pet Pest Prevention for a Healthy Pet

You may have heard that flea and tick prevention are crucial for dogs and cats, but do you know why? Petco is sharing why and how to prioritize pest prevention for your pet.

Updated on October 23rd, 2025

Protect Your Pet: Flea & Tick Control Solutions for Dogs & Cats

Learn how to remove flea and ticks. Petco has flea and tick removal services for dogs and cats. Get fleas and ticks removed at your neighborhood Petco.

Updated on April 9th, 2026

Your Cat's Best Life: Feeding, Health, Behavior & Home Guide

Learn how to care for your cat, recommended diet and grooming care. Find the right food, supplies and equipment at your neighborhood Petco.

Updated on April 9th, 2026

My cat still has fleas after Frontline. Can I reapply after 2 weeks?

Frontline has been around a long time now and I suspect there is some flea resistance to the product. I would recommend you use a different product like Program. Yes, you can do it now since it has been 2 weeks. ( https://www.amazon.co.uk/Program-Suspension-Small-Kittens-1-10lbs/dp/B00KF2X1BI/ref=sr_1_16?keywords=flea+cat&qid=1564665823&s=gateway&sr=8-16 ) Also, you need to be sure to treat the house or the fleas will keep causing an issue. This is the best product. ( https://www.amazon.co.uk/Virbac-Knockout-ES-Area-Treatment/dp/B00AT6FY6A/ref=sr_1_1?keywords=knockout+spray&qid=1564665743&s=gateway&sr=8-1 )

My cat has fleas. Is Frontline or Advantage better than Seargents?

I like advantage better than Frontline. That said, some veterinary office will sell flea products one unit (one month) at a time. They only require a physical exam once a year most likely, so they can establish a patient client relationship. I really like revolution or Comfortis for flea medicine but if you have to pick between advantage and frontline I prefer advantage. You could also alternate advantage one month, frontline one month then go back to advantage. Thank you for using Boop by Petco.

Can I use Frontline on my cat in heat with fleas, if pregnant?

Yes you can, strictly use the product recommended for cats. Other spot on may work better (like Stronghold), as fleas are getting resistant to frontline. Please do not hesitate to contact us again on the forum or by requesting a consultation if you have any more questions or to discuss it any further.

Cat's flea treatment not working. Can I safely apply Frontline now?

Since both Sentry and Frontline use the same active ingredient (fipronil) it is unlikely that you will see better protection switching to the Frontline. You will need to choose a product with a different ingredient, like Advantage or Revolution or a Seresto collar. If you choose to use another topical, I would recommend bathing your kitty today to remove any remnants of the Sentry, and wait 3 days to apply the next topical. It is important to wait after bathing so that the natural body oils have time to coat the skin to ensure adequate absorption. You do not need to wait or bathe to use a Seresto collar.

What are the best flea and tick prevention products for my cat?

Thanks for using Boop by Petco! In my opinion, the best two flea and tick preventative medications are Bravecto and Frontline plus. Any of those would be good options for him. Good luck and have a good night!