Fluoxetine Prescriptions for Small Animals & Other Pets | Petco

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Amitriptyline vs. Fluoxetine? Is one better or safer than the other for a cat? I'm not crazy about the idea of giving anti anxiety medication to my cat in the first place, so I want to make sure I'm giving her the safest one available.
Ultimately, this is a decision that really needs to be made by the prescribing veterinarian, as there may be good reasons for choosing one of these medications over the other for a particular patient. But in general, I can tell you that most veterinary behaviorists prefer SSRIs like fluoxetine over older TCAs like amytriptyline as a first-line choice for anxiety issues in cats because they tend to have fewer side effects and are better tolerated by most patients. I personally use fluoxetine frequently in both dogs and cats, and have not prescribed amirtiptyline in years. But again, your vet may have good reasons for whichever medication they recommend - just ask, and express your concerns if you have any so that the two of you can come to the best decision for Fiona :)
Updated on August 12th, 2025
Health & Wellbeing
Is 20mg of flouxetine a safe dose for a 47 lb. American Foxhound given once s day? Also is trazadone 50mg once daily safe to use with flouxetine?
Thank you for contacting Boop by Petco with your question. Twenty mg of fluoxetine given once daily to a 47lb dog is within the recommended dose range, so yes it is safe. The trazadone dose is also within the recommended dose range when used in combination with a selective serotonin reuptake inhibitor, which is the classification of fluoxetine. There is n increased risk of developing a disorder called serotonin syndrome when these two drugs are used together, but the lower dose range of trazadone is used when they are given together to try to prevent that. The normal dose range of trazadone is higher than what Hank is currently being given. I hope this helps!
Updated on August 12th, 2025
Health & Wellbeing
My yorkie was prescribed 5 mg of fluoxetine daily for severe separation anxiety. I’ve been breaking 10 mg capsules and wrapping the meds in meat, two meat balls per capsule. For convenience I’ve prepared up to ten balls in advance. It recently occurr
I'm not 100% sure about the stability of fluoxetine outside of the capsule, but as long as a capsule is not extended release I will sometimes recommend that people put the contents in a meatball like you describe for pets who are difficult to pill. I would be concerned about the stability of the drug in the meatball for 10 days however - it would probably be best to make each meatball daily and leave the remaining medication in the capsule or a dark plastic bag so it isn't exposed to light or oxygen. You may also want to ask your vet about having the medication compounded into a liquid suspension through a compounding pharmacy which might make it easier to squirt into a meatball and would result in more accurate dosing.
Updated on August 12th, 2025
Health & Wellbeing
My dog just got prescribed Prosac and I feel the dosage is too high. What is the recommended dosage? He is prescribed 60 mg twice a day and he is only 75 pounds
Hi there. The published dosage range for fluoxetine (Prozac) in dogs is 0.5 - 2 mg/kg once daily. 60 mg is within this range, but this medication is normally given only once daily. Your veterinarian may have had a specific reason for choosing to prescribe it twice daily in Saber's case, so if you're concerned, I would recommend calling to discuss your questions with your vet. He/she should be able to explain why they chose this dosage for Saber, or may opt to reduce it if it was an oversight :)
Updated on August 12th, 2025
Health & Wellbeing
Are there anti anxiety medications for dogs
Hi, thanks for using Boop by Petco! Yes, they are all human medications used off label in animals. There are long acting drugs like prozac, zoloft, clomicalm, etc and then short acting medications like trazadone, acepromazine, xanax, etc. These drugs need to be prescribed by your Vet and work best with behavioral training. I hope this helps and I wish you and Buddy the best!
Updated on August 12th, 2025