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It depends on the type of shampoo and how long ago the advantage was applied. But many medicated shampoos are designed to strip grease and keratin from the skin and those will certainly decrease the effectiveness of the advantage. If a medicated bath is necessary and it is close to time to reapply I would plan to reapply the advantage. Or speak to your vet about oral flea medications.
Updated on September 24th, 2025
Flea and tick shampoos are only a quick fix. They will not continue to repel or kill fleas. They are not recommended - any brand. The Antiparasitic/Antiseborrheic shampoo does not have the active ingredients that the Duoxo has. I'm not saying it won't work (it might) but I am not familiar with it.
My favorite brand is Duoxo. It comes in a shampoo that has chlorhexidine and climbazole that treats bacterial and fungal problems. However, if you are unable to find this or something similar at a pet store then any drug store is likely to have a chlorhexidine OR salicylic acid shampoo in their human shampoo section. I hope this helps! Best of luck and thank you for using Pet Coach.
Advantage works well for some areas of the US and some pets. If you are still finding fleas on Lucky in a week or two, you may need to try a prescription product sold by your vet. It can take 3 months or more of consistently treating the pets in a household and the home to get fleas under control.
Flea shampoo is not effective and should be avoided. here is the list of the best flea products on the market. Spot ons: Revoulution Advantage Advantage Multi Frontline (ticks as well) Tablets: Trifexis/comfortis Bravecto (ticks as well) Collar: Seresto ( (ticks as well) House spary: Indoorex