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Considering a Pitbull Mastiff mix? What should I know?

Updated on September 23rd, 2025

Pet's info: Dog | Mixed Breed Large (61lb +) | Male | 11 years and 1 month old | 105 lbs

My dog Mike is a cross bet. PIT & Mastiff, can you tell me anything about this combination. It seems they are getting more common.

1 Answer

Most Helpful Answer

Ana M, DVM

Answered By Ana M, DVM

Veterinarian

Published on June 20th, 2018

Thank you for submitting your question regarding Mike. This can be a hardy breed combination. The biggest problem I tend to see is joint disease (mainly arthritis) due to large size of these dogs. This can occur as the dog ages. Keeping the dog very lean throughout its life will help to protect the joints. The other big issue is that some of these dogs can be aggressive. So I think proper socialization and obedience training starting as pups is important. This helps to form a well adjusted dog. Most of them that j see are very sweet. I hope this information helps!
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