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How long does Heartgard Plus take to kill dog roundworms & hookworms?

Updated on September 23rd, 2025

Pet's info: Dog | Mixed Breed Small (up to 22lb) | Male | 3 months and 14 days old | 3 lbs

How long does it take for Heartgard PLUS to kill roundwords and hookworms in dogs?

1 Answer

Most Helpful Answer

Rodrigo Roca, DVM

Answered By Rodrigo Roca, DVM

Veterinarian

Published on September 7th, 2017

Hello, you should expect a die off period of 3-5 days after administration of the medication. Because it is administered orally, most roundworms and hookworms begin to die almost immediately, but it may take up to 3-5 days to have complete clearance of worms. You may recheck a stool sample in 10 days to ensure there are not more parasites noted. Hope this helps and best of luck.
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