My female dog has discharge, tired, and trouble walking. What's wrong?

Your poor pup! If she isn't spayed, I would be very concerned that she has a pyometra. This is an infection of the uterus that is fatal without treatment, and it would cause a white discharge as well as vomiting. It sounds like your vet may have been suspicious she had a pyometra and tried treating it medically with antibiotics and anti-inflammatory drugs. Unfortunately the medical route often isn't successful, and surgery is needed to treat it. This means spaying her. I would take her back into the vet immediately, as this is a medical emergency. Best of luck.

Some discharge is normal but it is generally clearish or slightly opaque. Vaginal discharge can indicate an infection in the uterus. I recommend to have her examined today in case this discharge is related to a uterine infection. Uterine infections can lead to a life threatening septicemia so it's best to play it safe. Best of luck.

Uh-oh, this is quite concerning. This could be vaginitis, but probably is a uterine infection (pyometra, open). This is an emergency and she needs to be seen by a vet preferably today. Your vet will give Daisy a thorough exam, and then probably will want to do an x-ray to verify his diagnosis. Treatment is surgery to remove the uterus with all the pus contained. Antibiotics sometimes work, however that would only delay the surgery as she will have another uterine infection when she has her next heat. Please take her to your veterinarian ASAP.

Hello, Tisay may be having an infection of her uterus (pyometra). She should be seen by a veterinarian today and may require surgery and medications to remove her uterus. A miscarriage typically does not cause bad smelling discharge although it can, but a pyometra may be far more common to cause the clinical signs your are seeing. Best of luck and hope this helps.

Those are definitely concerning symptoms that warrant getting her to the vet as soon as possible. If she's awake and alert, breathing normally, with pink gums like the picture, waiting until first thing tomorrow morning is likely ok, but I can't be sure something serious isn't going on from what you've described. The list of possible causes is long and varies from a minor soft tissue injury, to an orthopedic issue, or something life threatening like a twisted stomach or pyometra (very uncommon in spayed dogs).

It's a little difficult to see for certain in the picture, but I do see a fluid filled structure in the photo near the urinary bladder that certainly could be the uterus. In your final picture the discharge on the ground does not look what I would typically expect from vaginitis. You may want to get a third opinion from a veterinarian if you're concerned about going forward with surgery. If it is a uterine infection it is unlikely to clear with antibiotics alone and even if it does the infection returns with the next heat cycle, so I typically recommend surgery whenever I am concerned about a pyometra.

Unfortunately without seeing her in person, I can't say for certain if the white discharge and smell is a major concern. It could be a sign of a pyometra, and that is fatal without treatment. To be safe, I think it's best you take her into a vet now to get checked out. Best of luck.