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My puppy's urine culture shows WBCs, but no bacteria. What's wrong?

Updated on September 23rd, 2025

Pet's info: Dog | Mixed Breed Small (up to 22lb) | Female | spayed | 2 months and 18 days old | 29 lbs

My puppy had a urine culture done. And it turned out there was no bacteria growth. But there was white blood cells still in the urine. What does this mean?

1 Answer

Most Helpful Answer

Linda G,  MS, DVM

Answered By Linda G, MS, DVM

Veterinarian

Published on November 11th, 2019

Hello. Was this a sterile sample or one caught while she was urinating? Some white blood cells can be normal in the vaginal vault when collecting a free catch sample. It this was a sterile sample, then the white blood cells may be there because of inflammation not caused by infection. Often, these are very self-limiting, especially in puppies. Antibiotics are not required not recommended in these situations. Thanks for using Petco Pet Education Center, formerly Petcoach.
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