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My dog has seizures. Can spaying help reduce their frequency?

Updated on September 23rd, 2025

Pet's info: Dog | German Shepherd | Female | unspayed | 3 years and 5 months old | 58 lbs

Our 4 yr old shepherd has been having seizures since she was 1 1/2. She's on pheno and zonisamide. She has seizures every 4 to 6 wks. She has been having cluster's also, usually 3 or 4 in a 24hr period. She hasn't yet been spayed. Do you think getting her spayed will help reduce the seizures?

1 Answer

Most Helpful Answer

Andrea M. Brodie, DVM

Answered By Andrea M. Brodie, DVM

Veterinarian

Published on April 17th, 2017

One of the medical indications for spaying is indeed idiopathic seizures. Sexual hormones do have an impact on brain cell excitability and seizures. Estrogen is consistently found to increase susceptibility to seizures. So spaying is recommended.
Vote Icon1Pet Parents found this answer helpful

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