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Why is my dog scratching, biting, and has bumps after flea treatment?

Updated on September 23rd, 2025

Pet's info: Dog | Mixed Breed Medium (23 - 60lb) | Male | neutered | 4 years old | 35 lbs

My dog is a sharpei- basset hound mix. He is constantly biting himself and scratching. It feels like bumps underneath the skin and there is slight redness. He is treated for fleas and ticks. Please let me know what this could be.

2 Answers

Most Helpful Answer

Sara Farmer, DVM

Answered By Sara Farmer, DVM

Veterinarian

Published on April 27th, 2020

Allergies, either to something in the environment or less often to food, would be the most common cause of itching if Charlie is on a prescription flea preventative. He may have a secondary skin infection as well since you are feeling bumps. Mange can cause hair loss but usually isn’t significantly itchy.
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Related Answers from Veterinarians

  • Answered By Jeffrey Milner

    Veterinarian

    Published on April 25th, 2017

    I'm sorry to hear about Charlie's itchiness! Based on the description provided, the location of Charlies discomfort certainly does line up with a flea related reaction. The most common areas of flea reactions are at the base of the tail and along a dog's back. Other causes of itching and scratching include environmental allergies, food allergies, and atopic dermatitis. If Trifexis is being given on a monthly basis religiously, it certainly would lower the likelihood of a flea reaction. However, it certainly does not rule it out. I would recommend obtaining a flea comb and going over Charlie's skin carefully to look for both live and dead fleas, as well as flea dirt. If you find any, you may want to consider using a different medication as some preventatives tend to work better than others in particular geographic regions. In order to prevent Charlie from doing any harm to himself, you may want to consider getting a collar for him until the scratching has been resolved. Temporary ways to resolve scratching might be with benadryl, but if the situation is advanced this will usually not work. Often times, a stronger prescription drug may be required to get the situation under control. If you are able to determine without a doubt that fleas are not the issue, I would certainly plan a visit to the vet to let them have a look at Charlie.

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