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My dog still scratches on Apoquel. Can I use OTC allergy meds?

Updated on September 23rd, 2025

Pet's info: Dog | Chinese Shar-Pei | Female | spayed | 2 years old | 44 lbs

Our 2-year-old Shar-pei is taking a course of Apoquel along with her Bravecto. While Bravecto seems to work very well, as advertised, the Apoquel does not seem to work. Our Coco is still scratching, some licking, and shedding balls of hair. She eats Purina One. Would she be as well off taking over the counter allergy medicines like Benadryl, Claritin, etc.? Thank you for your time.

2 Answers

Most Helpful Answer

Laura Johnson VMD

Answered By Laura Johnson VMD

Veterinarian

Published on June 1st, 2018

Hi, thanks for using PetCoach!

While apoquel is a great drug to stop scratching and to help atopic dermatitis it doesn't do anything in the face of a skin infection. Coco should be checked to see if she now has a yeast and or bacterial skin infection. There is also the option of doing an injection for scratching called cytopoint, which lasts 30-60 days (dog dependent). I would also consider adding Omega 3 fish oils and changing her diet to a non-chicken based novel protein diet (try venison, lamb, fish). Claritin, benadryl and zyrtec can be sued in dogs, see links below:

https://www.petcoach.co/canigive/dog/benadryl/
https://www.petcoach.co/canigive/dog/zyrtec/
https://www.petcoach.co/canigive/dog/claritin/
https://www.vrshealth.com/canine-products/omegadog/
https://www.drsfostersmith.com/product/prod_display.cfm?pcatid=15235
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Related Answers from Veterinarians

  • Answered By Jenny, DVM

    Veterinarian

    Published on February 26th, 2018

    It does sound like allergies either from food or something in the environment.
    You can switch to a novel protein or hypoallergenic diet such as royal canine rabbit and potato or science diet D/D. The goal is to find a single carb and single protein to monitor ehat they eat. Treats also count and results take 4-8 weeks.
    You can also get a medicated shampoo to bathe weekly and add omega 3 fatty acids and fish oils tonthe diet to help
    If this does not help then you are left with medication. This can be given every day or even seasonally if needed to control symptoms. Apoquel is a good option to talk to your vet about or a stronger antihistamine such as hydroxyzine to help

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    1Pet Parents found this answer helpful

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