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Why is my active dog peeing spots with low blood cells & platelets?

Updated on September 23rd, 2025

Pet's info: Dog | Labrador Retriever | Male | neutered | 60 lbs

My Labrador has tested low in white blood cells and platelet. Red blood cells is at low side of the normal range. He left spot of his pee while he was sleeping. Other than that He is active and playful in daily life.Any problem?

1 Answer

Most Helpful Answer

Jacqueline Nobles, DVM, DACVECC

Answered By Jacqueline Nobles, DVM, DACVECC

Veterinarian, Board-Certified Emergency/Critical Care Specialist

Published on March 25th, 2017

You are describing pancytopenia which is a low red blood cell, white blood cell and platelet count. We see this disease process secondary to infectious diseases carried by ticks, toxins such as hormones or even secondary to some medications such as anti-inflammatories, primary diseases of the bone marrow and cancer. Unfortunately, it is a problem because if left untreated his platelet count will continue to drop resulting in bleeding and his low white blood cell count predisposes him to infection. He needs to be tested for tick borne disease and possibly have a bone marrow aspirate. In the meantime, your veterinarian may recommend treating him with doxycycline and prednisone.
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