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Should my puppy or dog get the Lyme vaccine and when is best?

Updated on September 23rd, 2025

Pet's info: Dog | Mixed Breed | Female | spayed | 1 year and 6 months old | 13 lbs

Do you recommend the Lyme vaccine? And if so at what age?

2 Answers

Most Helpful Answer

Laura Johnson VMD

Answered By Laura Johnson VMD

Veterinarian

Published on August 14th, 2017

Hi, thanks for using Petco Pet Education Center, formerly Petcoach!

There are a couple of drug companies that make a Lyme vaccine. Some are better than others. None are 100% protective. The Merek NOBIVAV is a good vaccine about 80% effective compared to other companies. Each company is labeled a bit differently for the youngest age to start the vaccine series, I usually recommend 12 weeks or older.

I recommend the Lyme vaccine with a good oral tick preventative in Lyme endemic areas

Hope this helps!
Vote Icon1Pet Parents found this answer helpful

Related Answers from Veterinarians

  • Answered By David Darvishian

    Veterinarian

    Hi and thanks for using Petco Pet Education Center, formerly Petcoach! Great questions. This actually depends on where you live and what exposure you and your veterinarian think Lexi will face in the future. Lyme disease is widespread and spreading more each year. Your veterinarian can actually show you the incidence of the Lyme disease in your immediate county or in areas where you might travel with Lexi. This decision can be made jointly with your veterinarian and based on what vaccine they use and recommend, it will have certain age requirements. Of course it's always best to start vaccines like this when they are puppies, but in Lexi's case you can start them now. She will need a series of 2 vaccines 3-4 weeks apart and she should be tested for exposure to the Lyme bacteria using an in house test that most vets run. Good luck with her. The other important point is to always use good flea and tick medicines to hopefully prevent flea/tick exposure and the resultant problems they cause.

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    0Pet Parents found this answer helpful

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