OTC flea treatment failed. Is it safe to use Frontline or Advantage?

It is safe to reapply the Frontline now, but in my experience, it doesn't have great flea protection. You may have better luck with Advantage products or a Seresto collar. The best flea protection is the prescription oral flea preventatives, like Bravecto or Nexgard.

The two treatments are not closely related but I would still recommend 7-10days before reapplying. You do not mention why you washed off the advantage but I would recommend combing with a flea comb to remove fleas in the meantime if still present. It may be worth considering using comfortis or capstar tablets if he does not tolerate spot on medications (it is often the carrier and not the active ingredient that pets are sensitive to)

Frontline doesn't always work unfortunately, but a flea shampoo is not likely to give you a better result. Instead I recommend using Advantage or Advocate spot on, Alternatively a comfortis tablet will do an excellent job as well. Do not bath her at least 3 days before and after you apply any spot on. As these flea treatment do not contain the same active ingredients as the frontline, they are safe to use at anytime you chose.

Over the counter flea products that are fine to use with sentinel include frontline plus, advantage and Advantix. Just be sure to not bathe your dog a couple days before or after applying any of those products as that can affect how effective they are.

Hi there. If Frontline is not working for your dog (which is sadly very common, in my experience), I would recommend using a different medication rather than reapplying a second dose. I normally recommend Nexgard, Bravecto, Simparica, or Credelio for fleas and ticks - all of these medications are safe and effective, and would be fine to give even if you applied Frontline 10 days ago.

Since both Sentry and Frontline use the same active ingredient (fipronil) it is unlikely that you will see better protection switching to the Frontline. You will need to choose a product with a different ingredient, like Advantage or Revolution or a Seresto collar. If you choose to use another topical, I would recommend bathing your kitty today to remove any remnants of the Sentry, and wait 3 days to apply the next topical. It is important to wait after bathing so that the natural body oils have time to coat the skin to ensure adequate absorption. You do not need to wait or bathe to use a Seresto collar.

Thanks for using Petco Pet Education Center, formerly Petcoach! Yes, you may in about 5-6 days. However, I would highly recommend you use a stronger and likely more efficacious product. There are plenty of flea products in the market and a lot of them are very effective. I prefer Bravecto and Frontline plus. You can pick one of those products. The nice thing about Bravecto is that it is very effective and it is only applied once every 3 months. You can also use a product called Capstar along with one of the previously mentioned products which can help kill a lot of fleas at once. Remember to vacuum all the surfaces that have contact with your pup regularly. This is very likely going to work well. Good luck and have a great day!