How do I manage my dog's epilepsy with Pexion and Phenobarbital?

I think many veterinarians would continue with both medications if the seizures were refractory to the first medication, but other times the goal is to try to transition from one anticonvulsant to another for various reasons. I would recommend asking the specialist or your veterinarian (whoever will be managing Jig’s seizures) what the long term plan is.

Thanks for using Petco Pet Education Center, formerly Petcoach! I do not think that you are being selfish at all. You care about him which is good. It is common for dogs with epilepsy to eventually need more medications added to their anti-seizure medication protocols. There are several anti-seizure medications that can be considered including phenobarbital, potassium bromide, Keppra, zonisamide, among many others. I would encourage you to discuss with your veterinarian about other anti-seizure medications. Often times dogs with epilepsy respond favorably to other medications. Good luck and have a great day!

Hi and thanks for using Petco Pet Education Center, formerly Petcoach! First, you are no bother at all-that's what's we are here for. Secondly, yes, you have a cause for concern. Any time a known epileptic starts seizing again, especially with any frequency, it's time for a vet visit asap. Likely they will do bloodwork to make sure nothing has changed since you were prescribed medications last. You did not mention any phenobarbital or potassium bromide for long term relief from seizures? Is your dog on any any antiseizure medications or just the Valium as needed? If he is not on medications currently they may very well start him on something for long term relief. If he already is-they will likely adjust the dosages. I hope this helps!

Hi and thanks for your request. The aim of the phenobarbital administration is to reduce effectively seizure frequency and severity. In my experience a frequency of once a month is fair and acceptable. Ideally Phenobarbital concentration should be checked 3 and 6 months after starting the treatment to monitor liver parameters and make sure the concentration of the drug in the blood is within therapeutic ranges. Dose could be even increased, but to be able to give you specific advices about it I would need to know Shadow's weight. Hope this answer was helpful, but please do not hesitate to contact us again on the forum or by requesting a consultation if you have any more questions or to discuss it any further. If this answer was helpful please let us know, this will be used to improve our service!

Thanks for using Petco Pet Education Center, formerly Petcoach! I'm so sorry to hear Hunter has been suffering from seizures. I would recommend reaching out to your regular veterinarian to discuss alterations in his medication protocol, as it is best for someone familiar with him, his case and his medications to make any alterations. Good luck!

I wish I had a little more information to help you with this question. IF she is just starting the medication and is on a loading dose then she could just be pretty drunk from the medication and may improve in time as her body adjusts. However, if she has been on the meds for a while and these are new changes then I would be concerned that this may be part of her underlying neurologic problem and not due to the meds. Regardless, I would encourage you to follow up with your veterinarian soon. In the meantime if you have other questions I would encourage you to request a consultation for more direct question and answer and “discussion” format. Best of luck and thank you for using Pet Coach.

Hello, thank you for using Petco Pet Education Center, formerly Petcoach. It is probably the overstimulation of her brain and the nerves that causes the breakthrough seizures. Exercise would not make her burn through the medication faster. It is really best to minimize excitement in any dog that has a history of seizures. That being said, if this is a new thing and it has been longer than 4 months since her last phenobarbital blood test, it would be best to go ahead and have that checked to see if the dosage needs to be adjusted. Hope this helps. Best wishes.