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Can I give my dog Diphenhist for an itchy, swollen paw? Is it safe?

Updated on September 23rd, 2025

Pet's info: Dog | Chihuahua | Female | spayed | 16 lbs

Itchy and miss colored, red ness and swolen . Taking her to vet Thursday, was wondering if I can give her a DIPHENHIST CAPSULE 25 MG CA thinking it would help ease itchyness and give her better sleep , is it safe ?

1 Answer

Most Helpful Answer

Sara Farmer, DVM

Answered By Sara Farmer, DVM

Veterinarian

Published on October 23rd, 2018

It does look like Toffee’s foot has been quite itchy, and she could have a secondary skin infection so I think it’s a great idea to see the vet. Unfortunately antihistamines usually do not help much with itchy skin in dogs, and this would be an overdose of diphenhydramine for a small dog like Toffee so I wouldn’t recommend giving it. You could try soaking her foot in some Epsom salts for 5-10 minutes to see if that helps with comfort.
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