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My dog has Addison's. Why are his thyroid meds not working, what's next?

Updated on September 23rd, 2025

Pet's info: Dog | Siberian Husky | Male | neutered | 110 lbs

Kaido is on Prednisone for Addison's Disease. He is also on Thyro tabs 0.8mg and just recently had a T4 done and his values are still very vey low after being on them for a year. Is it the Addisons or Pred counteracting the thyro tabs? And should I continue on with the Thyro tabs if it's not doing anything? Plus my vet told me to hold off on the Thyro tabs for another week but reconsider after. But if the Thyro tabs aren't working, what alternative does he have medication wise?

1 Answer

Most Helpful Answer

Linda G,  MS, DVM

Answered By Linda G, MS, DVM

Veterinarian

Published on April 22nd, 2020

Hello. Having a chronic condition like Addison's can stress the body & cause an artificial lowering of T4. You should insist that your veterinarian run a full thyroid panel, not just look at T4 which can be artificially lowered in many non hypothyroid situations. In addition, we generally treat Addison's disease with a mineral corticoid along with a glucocorticoid like prednisone. I would ask your vet about this as well. You need some more information on your pet. Thanks for contacting Petco Pet Education Center, formerly Petcoach.
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