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What's safe for hairless senior cat: fleas, mosquitos, no-see-ums?

Updated on September 23rd, 2025

Pet's info: Cat | Cornish Rex | Male | neutered | 14 years and 11 months old | 7.5 lbs

I have a cornish rex who is completely hairless, Frontline is said to be the least toxic , as we are traveling to key west and he needs something for mosquito, no see ums and fleas. I am terrified to us this because I always read that these meds can be toxic to exotics, but if he is bitten , and he will be , that can be scarier. He is 7lbs , super healthy and 15 years old.

1 Answer

Most Helpful Answer

Dr. Andrea

Answered By Dr. Andrea

Veterinarian

Published on June 24th, 2018

Frontline is very safe and well tolerated in cats. So is Advantage Multi- not Advantix- but Advantage Multi- (which also protects your cat against heart-worm disease and intestinal parasites as well)- these products are very safe for cats and they do very well for fleas and a little for ticks. Frontline does not not work for mosquitoes or no see ums. For that you need a product like a Seresto collar- whenever you get into these products the safety is a little less but Seresto is very safe and pretty well tolerated by most casts. It is not like the old flea collar that had Amitraz (those are NOT safe!).
I would suggest a Seresto collar and an oral Feline Heartgard chew or topical Advanatge Multi for your cat (combo of both). But you should check with your vet for more info for your particular cat.
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