Is it safe to give a feral cat Xanax to calm her for the vet?
It is unlikely that 1/4 of a 0.25mg alprazolam (Xanax) will sedate Pixie much, if at all. Always check with Pixie's vet prior to giving her any medication. Call the vet who will be examining her to ask if more effective oral sedatives (such as trazodone and/or gabapentin) can be prescribed in order to facilitate the vet visit. That said, use extreme caution giving any prescribed oral medication to Pixie since she is a feral cat. I would not recommend attempting to give her a pill if she is not up to date on her rabies vaccine due to the potential that she may bite you, intentionally or otherwise. If oral medication is not an option for one reason or another, you could either look into mobile vets able to come to your house, or expect to have her sedated at your vet if you are able to get her into a carrier. I hope that all goes well!
Updated on September 23rd, 2025