My cat hisses after other went outside. What can I do before vacation?

I suggest you try some Feliway diffusers and some environmental enrichment for them. You can refer to the links below. Feliway is like "happy cat" pheromones and really helps to calm cats down. You need to replace the diffusers every 30 days. There are many ways to do environmental enrichment. You can refer to the links below or do some additional research. ( https://www.feliway.com/ca_en/Products/FELIWAY-CLASSIC-Diffuser ) ( thedrakecenter.com/materials/environmental-enrichment-indoor-cats ) ( https://www.youtube.com/watch?v=AejmrLa_Cs4 ) If these things don't work then you should talk to your vet about getting some behavior modification medication for them (like Prozac). Hope this helps. Best wishes.

I would try a Feliway spray, diffuser or collar. It is a pheromone that helps with relaxation and anxiety. There are also supplements for anxiety. Set up separate areas for feeding and two litter boxes so they each have their own space with an area that they both have access to. Usually over time they will adjust if left alone. If she’s still aggressive there are prescription medications to give her for a little while to help her adjust so please discuss this with your veterinarian. Thanks for using Petco Pet Education Center, formerly Petcoach to help you care for Kaji.

Bathing all three cats may help but may not do much since it has been 9 days. Using Feliway wipes or sprays may help. And removing the cats from each other as you have been is the absolute right thing to do. Here’s an article with some other suggestions http://www.vetstreet.com/care/nonrecognition-aggression-in-cats Good luck. Thanks for using PetCoach.

Unfortunately it's going to take time. That said, there are a few things you can make sure of to help reduce stress, especially in a four-cat household (which is a lot!). Making sure each cat has their own space where they can eat, drink, play, observe, etc without the other cats bothering them can help reduce territorial disputes over these items. Pheromone collars and plug-ins (Feliway) can also be placed on stressed out individuals, or in shared rooms (since everyone seems to be stressed) to help reduce inter-cat aggression. Making sure to have at least one litter box per cat will also help reduce stress and competition over them, and reduce the chances of accidents elsewhere. Otherwise, continued slow introduction of the cats is best. If anyone starts to get agitated or too excited, removing them to let everyone calm down and settle back in is best. Continued aggression and upset may also need a trainer or veterinary behaviorist's help. That said, if your home is very small, four cats may just be too much for everyone to get comfortable.

I would recommend having a plug in in every room, you can use the sprays to spray areas where the cats seem to spend the most time - beds, blankets, hideaways etc. Cats are not typically sociable creatures and tend to prefer to spend time alone rather than with other cats, so ensuring that each cat has plenty of space and areas to retreat to is important. Make sure there are places up high they can escape to and private areas auch as boxes that they can hide in. Ensure there are plenty of litter trays - one per cat, plus an extra one, more if possible and that these are in different areas around the home. Also allow for separate feeding areas so that they are able to go and feed separately when they need to and there is no competition for food.

I can imagine it will be really hard for you to leave your cats, especially Jack! Yes, there are calming agents you can use. I recommend Feliway. It's a plug in diffuser that releases pheromones that help calm down cats. You can pair that with a Sentry calming collar, which also release pheromones when in contact with his skin. Your cats should be ok, they do adjust when their owners go on holiday for a bit. I would recommend as well leaving notice with your vet that your roommate has permission to seek veterinary treatment for them just in case something happens while you are gone. You also may want to have some funds set aside too in case of emergency. I hope this helps!

Gizmo can likely smell the vets off of DeEtta, she will think this is very odd and be unsure. This should only be a temporary situation and should resolve with time. You could try using a feliway diffuser to help settle them.