Do cat and dog pheromone diffusers interfere with each other?

No, Comfort Zone for cats will not have any effect on your dogs one way or the other. The pheromones for cats and dogs are species specific, so the cat version cannot be detected by dogs and vice versa.

The multi cat diffuser may give you slightly better results but they both will likely help. The diffusers are nice because it’s a constant infusion of the pheromone that occurs even when you are not home. Other things that can help Trixie to feel more calm are to provide climbing opportunities that satisfy her natural instincts. A tall cat tree or shelves mounted to the wall with a bed on top can help some cats feel more secure. Set aside 30 minutes a day for vigorous play as tiring her out may result in less anxiety. Royal Canin also makes a diet called Calm that affects the serotonin levels in the brain and some cats do very well on this diet. If she continues not to do well, medications may help. I hope this is helpful and please feel free to post any additional questions!

Usually, the diffusers work well if there is conflict happening in only one or two rooms, while a collar goes everywhere with the cat. I would just start with collar for Kovu and give him some time to see if it helps. Afterwards, if you notice specific problem areas, or the collar isn't working, switching to the plug-in diffusers long-term (say near a litterbox) may help as well. Both together may be a bit too much, while not increasing efficacy any.

Calming pheromone collars (Adaptil is one example) can be quite beneficial for some dogs and may not cause any changes in behavior/anxiety/stress in other dogs. The hard part with these products is that their efficacy for your individual dog is only established through trial and error. They are certainly not harmful, provided that you follow all directions on the packaging. Plug in pheromone diffusers are also available if you feel more comfortable using these products rather than a collar and can have a similar effect.

Great questions! Feliway contains synthesized cat pheromones, which helps cats with anxiety and stress, and can potentially help with urine marking and scratching. In my experience, it does help and I've seen very positive results in cats whose owners have used. The cat pheromones used in Feliway are odorless to us, but is a replication of a pheromone that cats leave when they are comfortable in their environment. Every time a cat rubs against an object, they are leaving this pheromone behind to mark their territory. Using Feliway can help a cat feel more calm and comfortable, and can reduce stress related behaviors such as urine marking. I recommend using the plug in diffuser of Feliway, which can be left on continuously and lasts about four weeks. You should start seeing results within a couple of days of using it, if not sooner. I hope this helps!

Pheromone products are not harmful or toxic. Alternatives would depend on what exactly you were using the pheromones to "treat". If it is to decrease aggression, behavioral modification may be required. For anxiety, you can use compression clothing, such as the ThunderShirt, as well as desensitization to the negative stimuli.

Good on you for introducing them slowly! I would use a DAP diffuser. This releases pheromones that help with anxiety in dogs. You can pain this with a Sentry calming collar for the dogs. When in contact with their skin, it also releases pheromones. This may help with their anxiety around the kittens. If this method doesn't help, I would take them into the vet to discuss using anti-anxiety drugs. Best of luck, I hope this helps!