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My cat is anxious and over-grooming. What medicine can help?

Updated on September 23rd, 2025

Pet's info: Cat | Domestic Shorthair | Female | spayed | 9 lbs

I have a cat with psychogenic allopecia. So far my vet has prescribed Ativan, with little apparent effect. Can you tell me what medication you think is most effective in calming a very anxious cat?

2 Answers

Most Helpful Answer

Jessica Keay, DVM

Answered By Jessica Keay, DVM

Veterinarian

Published on August 18th, 2017

I am sorry to hear about your kitty! Some of the most commonly used drugs to treat psychogenic alopecia in kitties include fluoxetine, amitryptylline, and clomipramine. We may sometimes use a supplement called Zylkene as well which can help decrease anxiety in some cats. True cases of psychogenic alopecia,however, are rare. It is much more common to have hair loss due to a skin disease/itching. If your vet hasn't done testing yet to ensure there isn't a cause for itching then I would consider this, or a referral to a veterinary dermatologist. You can read more about this condition and the possible causes/testing at http://www.veterinarypartner.com/Content.plx?P=A&S=0&C=0&A=2565.
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