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FRONTLINE Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs., 8 Treatments

FRONTLINE Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs., 8 Treatments


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12
$117.95
8
$92.14
6
$76.94
3
$38.94
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Description

Please note that the product information displayed is provided by manufacturers, suppliers and other third parties and is not independently verified by Petco.

FRONTLINE Plus Flea and Tick Treatment for Dogs and Cats is a fast-acting, long-lasting and waterproof flea and tick protection proven to kill fleas, flea eggs, lice and ticks. Designed for dogs and cats eight weeks of age and older. Stored in the oil glands of your pet's skin, one easy topical application works for 30 days.

  • - Provides fast-acting, long-lasting flea and tick protection for pets 8 weeks or older
  • - Kills adult fleas, ticks, chewing lice, mites, and flea eggs and larvae
  • - Waterproof 24 hours after application
  • - Easy to apply for once a month for lasting protection
  • - For best results, apply every month

Specifications

SKU3176431
Primary BrandFRONTLINE
Days to ShipShips Next Business Day

Additional Features

Personalized Item flagNo

Seller makes no warranty, expressed or implied, concerning the use of this product other than indicated on the label. Buyer assumes all risk of use and handling of this material when such use and handling are contrary to label instructions.

To apply, simply follow these instructions and repeat every 30 days: Remove one FRONTLINE Plus applicator by lifting and removing the plastic tab to expose foil backing. Then peel away the foil or use scissors to open. Open the applicator by holding upright with foil side toward you and snap applicator tip. Next, part your pet's hair between the shoulder blades. Place the applicator tip just above the skin and squeeze. Apply entire contents of the applicator in a single spot directly onto the animal's skin. Do not apply on top of the haircoat. Avoid contact with treated area until dry.

Do not use on pets under 8 weeks of age and follow weight guidelines.

Reviews

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5 stars

2874

4 stars

395

3 stars

129

2 stars

71

1 stars

395

Overall Rating

4.4
2290 out of 3864 (59%) reviewers recommend this product

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Most Helpful Favorable Review

Frontline Plus is #1

Italian Greyhound Mom

19 years ago

I have been using Frontline Plus for a couple of years and have yet to have an i...

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163 PEOPLE FOUND THIS HELPFUL

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5

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4

Most Helpful Critical Review

Not like it used to be

harrykat

14 years ago

I used to use Frontline Plus religiously on my dogs, but the last couple of year...

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122 PEOPLE FOUND THIS HELPFUL

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Rating
1 - 8 of 2883 Reviews
Most Recent

981 Ratings-Only Reviews

Doesn't work our dog still had fleas! Don't buy !

Beth

19 days ago
Veteran told us don't use this it doesn't work! And she was right! Our dog still had fleas!

No, I do not recommend this product.

Helpful?
Response from :
17 days ago
Frontline Team
Flea infestations can take up to three months to fully resolve because of the complexity of the flea life cycle. An infested home will have all four life stages present: eggs, larvae, pupae, and adult fleas. FRONTLINE® Brand Products kill adult fleas and help stop new eggs and larvae from developing, but they do not affect the eggs and larvae that are already in the environment.<br /><br />These early life stages must mature before they can be exposed to the product on your pet. As they hatch and develop, they will eventually jump onto your pet to feed, come into contact with the treatment, and be killed. This process takes time, which is why infestations do not clear up immediately.<br /><br />Consistent monthly use of FRONTLINE PLUS for Dogs is essential to break the cycle. All pets in the household should be treated, and outdoor areas may still pose a risk due to wildlife, which can carry fleas.<br /><br />Remember, even if you continue to see fleas, the product is working. It is killing adult fleas and helping prevent new generations from taking hold. Patience and consistency are key to fully clearing fleas from your home. To learn more about fleas and flea infestations, visit the FRONTLINE® website: https://frontline.com/about-fleas <img src="https://s3.amazonaws.com/stratos-logos/logos/frontline.png" alt="frontline" title="frontline" style="display: block !important; margin-top: 2em !important; border: 1px solid #ccc !important; padding: 2px !important; background-color: white !important;" /> <!--[if ReviewResponse]><![endif]-->
Response from petco.com:
17 days ago
Customer Care
We’re sorry to hear the product didn’t work as expected. Your feedback is very important, and we appreciate you sharing your experience. We’ll make sure it’s passed along, as it helps us improve and better serve pets and their families.

Where is my order?

Eddie

1 month ago
I ordered Front-line on 2 Nov 2025. I have not received email confirmation nor have I received two packages of Front-line? Please send me my order.

No, I do not recommend this product.

Helpful?

Frontline plus flea killer DIDN'T kill fleas!!

Justice

1 month ago
Frontline plus Flea/tick treatment wasn't work on my 18 lbs dog after topical used 12 hours! My dog has been healthy and he hasn't used any flea killer before. So hus fleas and himself should be sensitive BUT it's NOT at all!! Don't waste time and money in FRONTLINE!!!

No, I do not recommend this product.

Helpful?
Response from petco.com:
1 month ago
Customer Care
We appreciate your feedback regarding the Frontline Plus treatment. For specific concerns about product effectiveness, we recommend consulting with a veterinarian for expert advice. If you need further assistance, please reach out at petco.com/contact-us.

Great transaction, easy ordering and quick shippin

Kerri G

1 month ago
From beginning to end this was a positive experience. It was easy to order and shipping was very quick. Stress free transaction

Yes, I recommend this product.

Helpful?

Online Ordering

BethAnnC

1 month ago
Great value for price! Package arrived in a timely manner as well.

No, I do not recommend this product.

Helpful?

BEST SERVICE!!!

Johnny

1 month ago
I ordered these for my dog and in 2 days they were here

No, I do not recommend this product.

Helpful?

NOT Effective

DWS17

2 months ago
it did absolutely NOTHING for the fleas. Had no effect on the fleas whatsoever.

No, I do not recommend this product.

Helpful?
Response from :
2 months ago
Frontline Team
Do not reapply FRONTLINE® PLUS for Dogs for 30 days. Use once monthly to break the flea life cycle. You are likely seeing NEW fleas on your pet, which are jumping on your pet as it moves through infested areas in and around your home. Depending on the severity of the existing infestation, you may continue to see new fleas jumping on your pet for three months or more. To learn more about fleas and flea infestations, visit the FRONTLINE® website: https://frontline.com/about-fleas, or call 888-637-4251. <img src="https://s3.amazonaws.com/stratos-logos/logos/frontline.png" alt="frontline" title="frontline" style="display: block !important; margin-top: 2em !important; border: 1px solid #ccc !important; padding: 2px !important; background-color: white !important;" /> <!--[if ReviewResponse]><![endif]-->

Junk

Momo

3 months ago
I want to give zero star if I can. Don't waste your money on this junk. Did not kill any flea. My dog was going crazy with fleas running and biting him. Had to go to vet to get prescription Nexgard or Trifexis for him and it worked instantly. Petco manager refused to refund me claiming that I used 2/3 of the box. If I don't use it how do I know it's not working ?

No, I do not recommend this product.

Helpful?
Response from :
3 months ago
Frontline Team
Sorry for your experiences – flea issues are complex. You are likely seeing NEW fleas on your pet, which are jumping on your pet as it moves through infested areas in and around your home. Depending on the severity of the existing infestation, you may continue to see new fleas jumping on your pet for three months or more. <img src="https://s3.amazonaws.com/stratos-logos/logos/frontline.png" alt="frontline" title="frontline" style="display: block !important; margin-top: 2em !important; border: 1px solid #ccc !important; padding: 2px !important; background-color: white !important;" /> <!--[if ReviewResponse]><![endif]-->
1 - 8 of 2883 Reviews

Questions

1 - 10 of 33 Questions
Sort by: Newest Answers

It’s safe to use with my dog if I have kids at home that pet him all the time?

  1. Yes, just have them wash their hands if they touch the area. If kids are little, show them where to better pet the dog and tell them he has his flea medicine “right there”. 



I have a 7 year old Chihuahua that barely makes 5lbs. Is Frontline Plus ok for my dog.

  1. I think so but what I would do is just leave a little in the ampule, so he doesn’t get a dose big enough for a 15-20 lb dog



Is this also for prevention of fleas and ticks or is this soley treatment if a pet already has fleas?

  1. Frontline Plus is a prevention treatment. It will also treat a pet with a current flea/tick issue but it will not cure it. When I adopted my pup (with fleas), she started Frontline and had a special shampoo that we used once a week. If your pup has fleas/ticks, talk to your vet about the best way to treat. Frontline products should be used year-round to prevent future flea/tick problems. 



if dog has ticks will it kill them or is it to prevent ticks?

  1. The packaging says it will kill them.  I think you need the preventative after treating the dog, for long term use. 



What is the dose for a 150 pound dog? 2 large dog doses? 

  1. You can call Merial - they make Frontline - at 1-800-660-1842, Mon-Fri 8am to 7pm eastern time. Or ask your Vet.



Can Frontline cause seizures?

    Which product also works against mosquitos?

    1. I’ve used frontline and also brave to. Both work! 



    How many doses is this. One picture shows 3 another from the back shows 6. I cannot find this information anywhere in the description.

    1. They come in three dose and six dose packages.



    I used a cheaper brand on the cats. I bought this for the dog and have given the first treatment about 8 days ago. The fleas are still running all over her. adults and babies. i will treat the cats again and the dog again together in a month. help??

    1. I was using Frontline on my dog until I saw that it was not being effective on fleas when he would get them. My vet suggested I change to Simparica. It was the difference between night and day. What a difference; totally worth it even if it costs more.



    Is this a treatment or preventive ? Are they the same ?

    1. It’s a preventative.



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