Tri-Heart Plus must be administered monthly, preferably on the same date each month. If given seasonally, the first dose must be given within 30 days of the dog's first exposure to mosquitoes. The last dose must be given within 30 days after the dog's last exposure to mosquitoes. Most dogs like the taste of Tri-Heart Plus and will accept the chewable tablet as a treat. The chewable should be administered in a manner that encourages the dog to chew, rather than to swallow without chewing. Tri-Heart Plus Chewables may be broken into pieces and fed to dogs that normally swallow treats whole. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes after administration to ensure that part of the dose is not lost or rejected. If not entirely consumed, give another full-recommended dose as soon as possible.